Children Asymptomatic To COVID-19 Suffer From Inflammatory Syndrome: Study

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MIS-C: According to a study by Ermias D. Belay, Joseph Abrams, and Matthew E. Oster, published in JAMA Pediatrics on Tuesday, April 6, a case of Multisystem Inflammatory Syndrome (MIS-C) can be seen in young patients previously infected with COVID-19.

MIS-C is an inflammatory syndrome that is seen in those people who did not show any symptom, or only showed mild symptoms when they were infected with Covid-19. This inflammatory condition emerged in teenagers and children several weeks after getting infected with the coronavirus.

These people never had the COVID-19 symptoms at the time of the infection, the study published in JAMA Pediatrics says.

According to the study, the MIS-C is believed to mostly result from mild or asymptomatic COVID-19. It results in a hyper-inflammatory response in the body which appears when the bodies of the patients produce antibodies against the virus to their maximum capacity.

Here are the things we know about the new JAMA Paediatrics research.

  •  In the study done, 1733 patients with MIS-C were involved suffering from Gastrointestinal, mucocutaneous, or cardiovascular conditions and required intensive care.
  •  People of age 20 or younger participated in the study.
  •  The study was led by the Centers for Disease Control and Prevention, in which 75 per cent of the patients suffering from Covid-19 did not experience any symptoms.
  •  After two to five weeks, the patients got a serious condition of the Multisystem Inflammatory Syndrome and needed to be hospitalised. Their several organs especially the heart was affected.
  •  Experts have yet not been able to find out the reason behind a high rate of MIS-C in younger children.
  • This syndrome is rare but is very serious. 90 per cent of the young children who experience it suffer from problems in at least four organ system. 50 per cent of these people needed to be treated in ICUs.
  •  According to the study, people without COVID-19 symptoms experienced heart problems with a significantly higher percentage than the people who had COVID symptoms.
  •  About 37 per cent of patients were Hispanic, 34 per cent were Black and 20 per cent were white. Asian people comprised less than 1 per cent of the patients.
  • The majority of the patients were younger than 15, and children under 5 had the lowest rate of heart complications. They were more likely to not need intensive care.
  • Children of age 10 and older were more likely to develop conditions like shock, myocarditis (inflammation of heart muscle) and shock.

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